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Kérdezz-felelek
Köszönöm levelét. Örülök az eredménynek. Egyelőre az elkezdett szelén kezelést folytassa. Valószínűleg nem olvasták az alábbi (2018-ban megjelent) közleményt.
Röviden:
Title: Selenium and autoimmune diseases: a review article
Abstract
Selenium is an essential trace element with fundamental effects on human biology. Because selenium exists in component of selenoproteins, especially in active site of enzymes, it functions as a redox center in selenoenzyme and helps to control the intracellular redox state. Trace elements deficiency is not an uncommon finding in autoimmune diseases. This deficiency may be a consequence of autoimmune diseases or may contribute to their etiology. In regard to evidence that shows relevance between selenium deficiency and generation of reactive oxygen species and subsequent inflammation, reviewing the role of selenium in autoimmune diseases could help researchers about strategies that should be handled for managing the diseases. We intended to review the current literature regarding the role of selenium in different autoimmune diseases. Electronic databases (PubMed, Scopus, CINAHL, Science Direct, and Google Scholar) were searched using the suitable keywords for all autoimmune diseases and selenium from January 1980 to the 1st week of November 2017. The literature showed decreased serum levels of selenium in some autoimmune diseases (rheumatoid arthritis, autoimmune thyroiditis, Kashin–Beck Disease, systemic lupus erythematosus (SLE), Sjögren syndrome, Behcet`s disease, scleroderma, and celiac disease). Selenium deficiency especially has been linked to autoimmune thyroiditis. Selenium supplementation was found to have beneficial effects in management of rheumatoid arthritis, autoimmune thyroiditis, and scleroderma. Selenium administration may reduce the incidence and severity of certain autoimmune diseases through maintenance of thyroid function and the anti-inflammatory effect of selenium.
Selenium and Sjögren syndrome
Sjögren syndrome is a systemic disorder with an autoimmune nature (57). The lymphocytic infiltration of the exocrine glands is a remarkable manifestation of the disease. This leads to dryness of the eyes and mouth due to inflammation and resultant pathology of the lacrimal and salivary glands (58).
Studies about the impact of selenium on Sjögren syndrome show that serum selenium value is low in untreated patients, especially in older patients (59, 60).
Furthermore, a former study reported that treatment of Sjögren syndrome patients with selenium in combination with vitamin E led to halt disease progression for several years in some cases but not in all patients. Although studies show that selenium level is low in these patients, there is insufficient evidence about the effect of selenium on this syndrome. Therefore, a precise conclusion cannot be made at the moment. Future studies on the probable anti-inflammatory effect of selenium in preventing the progression of this condition are required.
A D3 vitamin szükséglet télen 3000NE/nap, a Szelén50 ug/nap.
A Salvus viz jódot valóban tartalmaz tartalmaz, de nagyon keveset, ezért fogyaszthatja.
Kontrrollra várom, jó egészséget kívánok,
tisztelettel: